Tuesday, 27 December 2011

Copalspir




Copalspir may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Copalspir



Spiramycin

Spiramycin is reported as an ingredient of Copalspir in the following countries:


  • Italy

International Drug Name Search

Friday, 23 December 2011

Betahistine Walmark




Betahistine Walmark may be available in the countries listed below.


Ingredient matches for Betahistine Walmark



Betahistine

Betahistine dihydrochloride (a derivative of Betahistine) is reported as an ingredient of Betahistine Walmark in the following countries:


  • Poland

  • Slovakia

International Drug Name Search

Wednesday, 21 December 2011

Starpod




Starpod may be available in the countries listed below.


Ingredient matches for Starpod



Cefpodoxime

Cefpodoxime is reported as an ingredient of Starpod in the following countries:


  • India

International Drug Name Search

Thursday, 15 December 2011

Kinin Recip




Kinin Recip may be available in the countries listed below.


Ingredient matches for Kinin Recip



Quinine

Quinine hydrochloride (a derivative of Quinine) is reported as an ingredient of Kinin Recip in the following countries:


  • Sweden

International Drug Name Search

Tuesday, 13 December 2011

Sesugium




Sesugium may be available in the countries listed below.


Ingredient matches for Sesugium



Timepidium Bromide

Timepidium Bromide is reported as an ingredient of Sesugium in the following countries:


  • Japan

International Drug Name Search

Monday, 12 December 2011

Segurite




Segurite may be available in the countries listed below.


Ingredient matches for Segurite



Levonorgestrel

Levonorgestrel is reported as an ingredient of Segurite in the following countries:


  • Argentina

International Drug Name Search

Friday, 9 December 2011

Allecet




Allecet may be available in the countries listed below.


Ingredient matches for Allecet



Cetirizine

Cetirizine dihydrochloride (a derivative of Cetirizine) is reported as an ingredient of Allecet in the following countries:


  • South Africa

International Drug Name Search

Monday, 5 December 2011

Dexametonal




Dexametonal may be available in the countries listed below.


Ingredient matches for Dexametonal



Dexamethasone

Dexamethasone 21-acetate (a derivative of Dexamethasone) is reported as an ingredient of Dexametonal in the following countries:


  • Brazil

International Drug Name Search

Sunday, 4 December 2011

Methenamine




In some countries, this medicine may only be approved for veterinary use.


In the US, Methenamine (methenamine systemic) is a member of the drug class urinary anti-infectives and is used to treat Bladder Infection and Prevention of Bladder infection.

US matches:

  • Methenamine

  • Methenamine/Sodium Biphosphate

  • Methenamine/Sodium Phosphate

  • Methenamine Hippurate

  • Methenamine Mandelate

  • Methenamine and Methenamine Salts

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

J01XX05

CAS registry number (Chemical Abstracts Service)

0000100-97-0

Chemical Formula

C6-H12-N4

Molecular Weight

140

Therapeutic Categories

Antibacterial

Urinary tract antiseptic

Chemical Name

1,3,5,7-Tetraazatricyclo[3.3.1.13,7]decane

Foreign Names

  • Methenaminum (Latin)
  • Methenamin (German)
  • Méthénamine (French)
  • Metenamina (Spanish)

Generic Names

  • Metenamina (OS: DCIT)
  • Méthénamine (OS: DCF)
  • E 239 (IS)
  • Hexamine (IS)
  • Urometine (IS)
  • Urotropin (IS)
  • Hexamethylentetraminum (PH: ÖAB 2009)
  • Methenamin (PH: Ph. Eur. 6)
  • Methenamine (PH: BP 2010, USP 32, Ph. Eur. 6)
  • Méthénamine (PH: Ph. Eur. 6)
  • Methenaminum (PH: Ph. Helv. 8, Ph. Eur. 6)
  • Formanol (IS)
  • Hexacitrol (IS)
  • Neotramin (IS)
  • Uropurgol (IS)
  • Esametilentetrammina anidrometilencitrato (PH: F.U. VIII)
  • Methenamine Hippurate (OS: BAN, USAN)
  • Hexamine Hippurate (IS)
  • Hippramine (IS)
  • R 657 (IS)
  • Methenamine Hippurate (PH: USP 32)
  • Hexamine Mandelate (OS: JAN)
  • Methenamine Mandelate (PH: USP 32)

Brand Names

  • Antihydral
    Iromedica, Switzerland; Robugen, Germany; Robugen, Luxembourg


  • Neturone
    Liba, Turkey


  • Pedipur
    Prolab, Poland


  • Stoppot
    Parafarm, Poland


  • Taubenheil (veterinary use)
    Roenfri, Germany


  • Helpa
    Adeka, Turkey


  • Purinol
    Yeni, Turkey


  • Uron
    Eras, Turkey


  • Haiprex
    3M, Iceland; Meda, Denmark


  • Hipeksal
    Leiras, Finland


  • Hippurin
    Yeni, Turkey


  • Hiprex
    3M, Costa Rica; 3M, Dominican Republic; 3M, Finland; 3M, Guatemala; 3M, Honduras; 3M, Israel; 3M, Kenya; 3M, Luxembourg; 3M, Morocco; 3M, Panama; 3M, Philippines; 3M, El Salvador; 3M, Zimbabwe; Douglas, New Zealand; iNova Pharmaceuticals, Australia; Meda, United Kingdom; Meda, Norway; Meda, Sweden; Sanofi-Aventis, United States


  • Hip-Rex
    Marion Merrell Dow, United States


  • Methenamine Hippurate
    CorePharma, United States


  • Urex
    County Line Pharmaceuticals, United States


  • Mandelamine
    Pfizer, Belize; Pfizer, Costa Rica; Pfizer, Guatemala; Pfizer, Honduras; Pfizer, Nicaragua; Pfizer, Panama; Pfizer, El Salvador; Pfizer, Venezuela; Warner Chilcott, United States


  • Manuprin
    Yeni, Turkey


  • Mesulfin (Methenamine and Sulfamethizole (veterinary use))
    Fort Dodge Animale Health, United States


  • Methenamine CF
    Centrafarm, Netherlands


  • Methenamine Mandelate
    Actavis, United States; Rugby, United States


  • Reflux
    ACE, Netherlands

International Drug Name Search

Glossary

BANBritish Approved Name
DCFDénomination Commune Française
DCITDenominazione Comune Italiana
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Friday, 2 December 2011

Flemex




Flemex may be available in the countries listed below.


Ingredient matches for Flemex



Carbocisteine

Carbocisteine is reported as an ingredient of Flemex in the following countries:


  • Myanmar

  • South Africa

  • Vietnam

International Drug Name Search

Sunday, 27 November 2011

Trimetazidin HG. Pharm




Trimetazidin HG. Pharm may be available in the countries listed below.


Ingredient matches for Trimetazidin HG. Pharm



Trimetazidine

Trimetazidine dihydrochloride (a derivative of Trimetazidine) is reported as an ingredient of Trimetazidin HG. Pharm in the following countries:


  • Vietnam

International Drug Name Search

Tuesday, 22 November 2011

Adco-Quinaretic




Adco-Quinaretic may be available in the countries listed below.


Ingredient matches for Adco-Quinaretic



Hydrochlorothiazide

Hydrochlorothiazide is reported as an ingredient of Adco-Quinaretic in the following countries:


  • South Africa

Quinapril

Quinapril is reported as an ingredient of Adco-Quinaretic in the following countries:


  • South Africa

International Drug Name Search

Saturday, 19 November 2011

Paramolan




Paramolan may be available in the countries listed below.


Ingredient matches for Paramolan



Paracetamol

Paracetamol is reported as an ingredient of Paramolan in the following countries:


  • Israel

International Drug Name Search

Friday, 18 November 2011

Quinovid




Quinovid may be available in the countries listed below.


Ingredient matches for Quinovid



Ofloxacin

Ofloxacin is reported as an ingredient of Quinovid in the following countries:


  • Indonesia

International Drug Name Search

Wednesday, 16 November 2011

Thyradin




Thyradin may be available in the countries listed below.


Ingredient matches for Thyradin



Levothyroxine

Levothyroxine sodium salt (a derivative of Levothyroxine) is reported as an ingredient of Thyradin in the following countries:


  • Japan

International Drug Name Search

Saturday, 12 November 2011

Uroprot




Uroprot may be available in the countries listed below.


Ingredient matches for Uroprot



Mesna

Mesna is reported as an ingredient of Uroprot in the following countries:


  • Chile

International Drug Name Search

Tuesday, 8 November 2011

Stabisol




Stabisol may be available in the countries listed below.


Ingredient matches for Stabisol



Hetastarch

Hetastarch is reported as an ingredient of Stabisol in the following countries:


  • Estonia

  • Lithuania

  • Russian Federation

  • Vietnam

International Drug Name Search

Monday, 7 November 2011

Paracetamol-1A Pharma




Paracetamol-1A Pharma may be available in the countries listed below.


Ingredient matches for Paracetamol-1A Pharma



Paracetamol

Paracetamol is reported as an ingredient of Paracetamol-1A Pharma in the following countries:


  • Germany

International Drug Name Search

Wednesday, 2 November 2011

Invega Sustenna




In the US, Invega Sustenna (paliperidone systemic) is a member of the drug class atypical antipsychotics and is used to treat Schizophrenia.

US matches:

  • Invega Sustenna

Ingredient matches for Invega Sustenna



Paliperidone

Paliperidone is reported as an ingredient of Invega Sustenna in the following countries:


  • United States

International Drug Name Search

Tuesday, 1 November 2011

Ceftriaxona Biol




Ceftriaxona Biol may be available in the countries listed below.


Ingredient matches for Ceftriaxona Biol



Ceftriaxone

Ceftriaxone disodium salt (a derivative of Ceftriaxone) is reported as an ingredient of Ceftriaxona Biol in the following countries:


  • Argentina

International Drug Name Search

Friday, 28 October 2011

Relistor




In the US, Relistor (methylnaltrexone systemic) is a member of the drug class peripheral opioid receptor antagonists and is used to treat Constipation - Chronic and Constipation - Drug Induced.

US matches:

  • Relistor

UK matches:

  • Relistor (SPC)

Ingredient matches for Relistor



Methylnaltrexone

Methylnaltrexone Bromide is reported as an ingredient of Relistor in the following countries:


  • Australia

  • Austria

  • Canada

  • Denmark

  • Germany

  • Ireland

  • Netherlands

  • Norway

  • Spain

  • Sweden

  • Switzerland

  • United Kingdom

  • United States

International Drug Name Search

Glossary

SPC Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Saturday, 22 October 2011

Brantil




Brantil may be available in the countries listed below.


Ingredient matches for Brantil



Etilefrine

Etilefrine hydrochloride (a derivative of Etilefrine) is reported as an ingredient of Brantil in the following countries:


  • Japan

International Drug Name Search

Friday, 21 October 2011

Megestrol




In some countries, this medicine may only be approved for veterinary use.


In the US, Megestrol (megestrol systemic) is a member of the following drug classes: hormones/antineoplastics, progestins and is used to treat Abnormal Uterine Bleeding, AIDS Related Wasting, Anorexia, Breast Cancer - Palliative, Cachexia, Endometrial Cancer, Endometrial Hyperplasia, Hot Flashes and Weight Loss.

US matches:

  • Megestrol

  • Megestrol Suspension

  • Megestrol Acetate

  • Megestrol Tablets

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

G03AC05,G03DB02,L02AB01

CAS registry number (Chemical Abstracts Service)

0003562-63-8

Chemical Formula

C22-H30-O3

Molecular Weight

342

Therapeutic Category

Progestin

Chemical Name

Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-

Foreign Names

  • Megestrolum (Latin)
  • Megestrol (German)
  • Mégestrol (French)
  • Megestrol (Spanish)

Generic Names

  • Megestrol (OS: BAN)
  • Mégestrol (OS: DCF)
  • Megoestrel (IS)
  • Megestrol Acetate (OS: BANM, USAN)
  • BDH 1298 (IS)
  • SC 10363 (IS)
  • Megestrol Acetate (PH: BP 2010, USP 32, Ph. Eur. 6)
  • Megestroli acetas (PH: Ph. Eur. 6)

Brand Names

  • Endace
    Samarth, India


  • Megace
    Abeefe Bristol-Myers Squibb, Peru; Bristol-Myers Squibb, Colombia; Bristol-Myers Squibb, Tunisia


  • Megestrol
    Servycal, Peru


  • Acestrol
    Almirall, Portugal


  • Alopectyl (veterinary use)
    Vetoquinol, Netherlands


  • Anestryl (veterinary use)
    Sogeval, Netherlands


  • Apo-Megestrol
    Apotex, Canada; Apotex, Singapore


  • Borea
    Madaus, Spain; Onko-Koçsel, Turkey


  • Cachexan
    Polfarmex, Poland


  • Canipil (veterinary use)
    Véto-Centre, France


  • Chronopil (veterinary use)
    Ceva, Belgium


  • De Poezepil (veterinary use)
    A.S.T. farma B.V, Netherlands


  • Derma Chat (veterinary use)
    Novartis Santé Animale, France


  • Dogalact (Megestrol and Danazol (veterinary use))
    Laboratoire Vétoquinol, France


  • Eczederm (veterinary use)
    A.S.T. farma B.V, Netherlands


  • Estropill (veterinary use)
    Intervet, Italy


  • Féliderm (veterinary use)
    Véto-Centre, France


  • Felipil (veterinary use)
    Véto-Centre, France


  • Maygace Altas Dosis
    Bristol-Myers Squibb, Spain


  • Maygace
    Bristol-Myers Squibb, Spain


  • Megace
    Bristol Meyers Squibb, Latvia; Bristol-Myers Squibb, Australia; Bristol-Myers Squibb, Bosnia & Herzegowina; Bristol-Myers Squibb, Belgium; Bristol-Myers Squibb, Canada; Bristol-Myers Squibb, Cote D'ivoire; Bristol-Myers Squibb, Chile; Bristol-Myers Squibb, China; Bristol-Myers Squibb, Czech Republic; Bristol-Myers Squibb, Denmark; Bristol-Myers Squibb, Algeria; Bristol-Myers Squibb, Estonia; Bristol-Myers Squibb, Finland; Bristol-Myers Squibb, France; Bristol-Myers Squibb, Gabon; Bristol-Myers Squibb, United Kingdom; Bristol-Myers Squibb, Guinea; Bristol-Myers Squibb, Greece; Bristol-Myers Squibb, Hong Kong; Bristol-Myers Squibb, Hungary; Bristol-Myers Squibb, Indonesia; Bristol-Myers Squibb, Ireland; Bristol-Myers Squibb, Italy; Bristol-Myers Squibb, Lithuania; Bristol-Myers Squibb, Luxembourg; Bristol-Myers Squibb, Mali; Bristol-Myers Squibb, Mauritius; Bristol-Myers Squibb, Niger; Bristol-Myers Squibb, Norway; Bristol-Myers Squibb, New Zealand; Bristol-Myers Squibb, Philippines; Bristol-Myers Squibb, Poland; Bristol-Myers Squibb, Portugal; Bristol-Myers Squibb, Romania; Bristol-Myers Squibb, Serbia; Bristol-Myers Squibb, Sweden; Bristol-Myers Squibb, Singapore; Bristol-Myers Squibb, Slovenia; Bristol-Myers Squibb, Slovakia; Bristol-Myers Squibb, Senegal; Bristol-Myers Squibb, Chad; Bristol-Myers Squibb, Togo; Bristol-Myers Squibb, Thailand; Bristol-Myers Squibb, Turkey; Bristol-Myers Squibb, Taiwan; Bristol-Myers Squibb, United States; Bristol-Myers Squibb, Venezuela; Euro, Netherlands; Par, United States; PharmaSwiss, Croatia (Hrvatska)


  • Megacorp
    Panalab, Argentina


  • Megalia
    Vipharm, Poland


  • Megaplex
    Combiphar, Indonesia; Pharmachemie, Indonesia; Pharmachemie, Taiwan; Teva, Czech Republic; Teva, Latvia; Teva, Slovakia


  • Megecat (veterinary use)
    Vetoquinol, Belgium; Vetoquinol, Switzerland


  • Mégécat (veterinary use)
    Laboratoire Vétoquinol, France


  • Megefel (veterinary use)
    Eurovet, Netherlands


  • Megefren
    Merck Genericos, Spain


  • Megejohn
    Johnson, Taiwan


  • Mégépil Chat (veterinary use)
    Omega Pharma France, France


  • Megesin
    Actavis, Hungary; Sindan, Poland; Sindan, Romania; Sindan, Slovakia


  • Megestat
    Bristol-Myers Squibb, Brazil; Bristol-Myers Squibb, Switzerland; Bristol-Myers Squibb, Germany


  • Megestil
    Teofarma, Italy


  • Megestoral (veterinary use)
    A.S.T. farma B.V, Netherlands


  • Megestrol Acetate
    Apotex, United States; Morton Grove, United States; Par, United States; Roxane, United States; Teva USA, United States


  • Megestrol
    Pharmachemie, Netherlands


  • Megestrol (veterinary use)
    Ceva, Netherlands


  • Megestrolo PH&T
    PH&T, Italy


  • Megostat
    Bristol-Myers Squibb, Bosnia & Herzegowina; PharmaSwiss, Croatia (Hrvatska)


  • Meltonar
    Teva, Argentina


  • Mestrel
    Chile, Chile; Lemery, Mexico


  • Milopect (veterinary use)
    Ceva, Netherlands


  • Minipil (veterinary use)
    Ceva, Netherlands


  • Ovaban (veterinary use)
    Schering-Plough Animal Health, United States


  • Ovarid (veterinary use)
    Jurox, Australia; Schering-Plough, Ireland; Schering-Plough Animal Health, South Africa; Schering-Plough Veterinary, United Kingdom


  • Ovasteryl (veterinary use)
    Vetoquinol, Netherlands


  • Pilucalm (veterinary use)
    Novartis Santé Animale, France


  • Piludog (veterinary use)
    Companhia Portuguesa de Higiene Pharma, Portugal


  • Suppress (veterinary use)
    Jurox, New Zealand


  • Varigestrol
    Varifarma, Argentina

International Drug Name Search

Glossary

BANBritish Approved Name
BANMBritish Approved Name (Modified)
DCFDénomination Commune Française
ISInofficial Synonym
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Risperidona Alter




Risperidona Alter may be available in the countries listed below.


Ingredient matches for Risperidona Alter



Risperidone

Risperidone is reported as an ingredient of Risperidona Alter in the following countries:


  • Portugal

  • Spain

International Drug Name Search

Tuesday, 18 October 2011

Xalkori


Xalkori is a brand name of crizotinib, approved by the FDA in the following formulation(s):


XALKORI (crizotinib - capsule; oral)



  • Manufacturer: PFIZER

    Approval date: August 26, 2011

    Strength(s): 200MG, 250MG [RLD]

Has a generic version of Xalkori been approved?


No. There is currently no therapeutically equivalent version of Xalkori available.


Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Xalkori. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents


Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.




  • Aminoheteroaryl compounds as protein kinase inhibitors
    Patent 7,230,098
    Issued: June 12, 2007
    Inventor(s): Cui; Jingrong Jean & Bhumralkar; Dilip & Botrous; Iriny & Chu; Ji Yu & Funk; Lee A. & Hanau; Cathleen Elizabeth & Harris; G. Davis & Jia; Lei & Johnson; Joanne & Kolodziej; Stephen A. & Kung; Pei-Pei & Li; Xiaoyuan (Sharon) & Lin; Jason (Qishen) & Meng; Jerry Jialun & Nambu; Mitchel
    Assignee(s): Sugen, Inc.
    Aminopyridine and aminopyrazine compounds of formula (1), compositions including these compounds, and methods of their use are provided. Preferred compounds of formula 1 have activity as protein kinase inhibitors, including as inhibitors of c-MET
    Patent expiration dates:

    • March 1, 2025
      ✓ 
      Drug substance




  • Method of treating abnormal cell growth
    Patent 7,825,137
    Issued: November 2, 2010
    Inventor(s): Christensen; James Gail & Zou; Yahong
    Assignee(s): Pfizer Inc.
    The present invention relates to the use of (R)-3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine, a novel c-Met/HGFR inhibitor, for treating abnormal cell growth in mammals. In particular, the invention provides methods of treating mammals suffering from cancer.
    Patent expiration dates:

    • May 12, 2027
      ✓ 
      Patent use: TREATMENT OF A CANCER MEDIATED BY AN ANAPLASTIC LYMPHOMA KINASE (ALK)




  • Enantiomerically pure aminoheteroaryl compounds as protein kinase inhibitors
    Patent 7,858,643
    Issued: December 28, 2010
    Inventor(s): Cui; Jingrong Jean & Funk; Lee Andrew & Jia; Lei & Kung; Pei-Pei & Meng; Jerry Jialun & Nambu; Mitchell David & Pairish; Mason Alan & Shen; Hong & Tran-Dube; Michelle
    Assignee(s): Agouron Pharmaceuticals, Inc.
    Enantiomerically pure compound of formula 1 are provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.
    Patent expiration dates:

    • October 8, 2029
      ✓ 
      Drug substance
      ✓ 
      Drug product



Related Exclusivities

Exclusivity is exclusive marketing rights granted by the FDA upon approval of a drug and can run concurrently with a patent or not. Exclusivity is a statutory provision and is granted to an NDA applicant if statutory requirements are met.

  • Exclusivity expiration dates:
    • August 26, 2016 - NEW CHEMICAL ENTITY

    • August 26, 2018 - ORPHAN DRUG EXCLUSIVITY

See also...

  • Xalkori Consumer Information (Drugs.com)
  • Xalkori Consumer Information (Wolters Kluwer)
  • Xalkori Consumer Information (Cerner Multum)
  • Crizotinib Consumer Information (Wolters Kluwer)
  • Crizotinib Consumer Information (Cerner Multum)

Saturday, 15 October 2011

rosiglitazone and glimepiride


glye-MEP-ir-ide, roe-zi-GLI-ta-zone MAL-ee-ate


Oral route(Tablet)

May cause or worsen congestive heart failure, is not recommended in patients with symptomatic heart failure, and is contraindicated in patients with established NYHA Class III or IV heart failure. Monitor patients for signs and symptoms of heart failure after initiation or dose increases and if heart failure occurs, consider dose reducing or discontinuing rosiglitazone maleate and manage according to current standards of care. A meta-analysis of 52 clinical trials (mean duration 6 months; 16,995 total patients), most of which compared rosiglitazone to placebo, showed rosiglitazone to be associated with a statistically significant increased risk of myocardial infarction. Because of the potential increased risk of myocardial infarction, rosiglitazone maleate/glimepiride is available only through a restricted distribution program called the AVANDIA-Rosiglitazone Medicines Access Program. Both prescribers and patients need to enroll in the program. To enroll, call 1-800-AVANDIA or visit www.AVANDIA.com .



Commonly used brand name(s)

In the U.S.


  • Avandaryl

Available Dosage Forms:


  • Tablet

Therapeutic Class: Antidiabetic


Chemical Class: 2nd Generation Sulfonylurea


Uses For rosiglitazone and glimepiride


Rosiglitazone and glimepiride combination is used to treat a type of diabetes mellitus called type 2 diabetes. It is used together with a proper diet and exercise to help control blood sugar levels.


Rosiglitazone helps your body use insulin better. Glimepiride stimulates the release of insulin from the pancreas which will help your body turn food into energy.


rosiglitazone and glimepiride is only available through a restricted access program. Doctors who are enrolled in the program can write a prescription for rosiglitazone and glimepiride.


Before Using rosiglitazone and glimepiride


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For rosiglitazone and glimepiride, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to rosiglitazone and glimepiride or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of rosiglitazone and glimepiride combination in the pediatric population. Safety and efficacy have not been established.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of rosiglitazone and glimepiride combination in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving rosiglitazone and glimepiride combination.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking rosiglitazone and glimepiride, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using rosiglitazone and glimepiride with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Alatrofloxacin

  • Balofloxacin

  • Ciprofloxacin

  • Clinafloxacin

  • Disopyramide

  • Enoxacin

  • Fleroxacin

  • Flumequine

  • Gatifloxacin

  • Gemifloxacin

  • Grepafloxacin

  • Levofloxacin

  • Lomefloxacin

  • Moxifloxacin

  • Norfloxacin

  • Ofloxacin

  • Pefloxacin

  • Prulifloxacin

  • Rufloxacin

  • Sparfloxacin

  • Temafloxacin

  • Tosufloxacin

  • Trovafloxacin Mesylate

  • Voriconazole

Using rosiglitazone and glimepiride with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Acebutolol

  • Aceclofenac

  • Acemetacin

  • Alclofenac

  • Alprenolol

  • Apazone

  • Atenolol

  • Benoxaprofen

  • Betaxolol

  • Bevantolol

  • Bisoprolol

  • Bitter Melon

  • Bromfenac

  • Bucindolol

  • Bufexamac

  • Carprofen

  • Carteolol

  • Carvedilol

  • Celiprolol

  • Clometacin

  • Clonixin

  • Clorgyline

  • Dexketoprofen

  • Diclofenac

  • Diflunisal

  • Dilevalol

  • Dipyrone

  • Droxicam

  • Esmolol

  • Etodolac

  • Etofenamate

  • Felbinac

  • Fenbufen

  • Fenofibrate

  • Fenoprofen

  • Fentiazac

  • Fenugreek

  • Floctafenine

  • Fluconazole

  • Flufenamic Acid

  • Flurbiprofen

  • Gemfibrozil

  • Glucomannan

  • Guar Gum

  • Ibuprofen

  • Indomethacin

  • Indoprofen

  • Iproniazid

  • Isocarboxazid

  • Isoxicam

  • Ketoprofen

  • Ketorolac

  • Labetalol

  • Levobunolol

  • Lornoxicam

  • Meclofenamate

  • Mefenamic Acid

  • Meloxicam

  • Mepindolol

  • Metipranolol

  • Metoprolol

  • Moclobemide

  • Nabumetone

  • Nadolol

  • Naproxen

  • Nebivolol

  • Nialamide

  • Niflumic Acid

  • Nimesulide

  • Oxaprozin

  • Oxprenolol

  • Oxyphenbutazone

  • Pargyline

  • Penbutolol

  • Phenelzine

  • Phenylbutazone

  • Pindolol

  • Pirazolac

  • Piroxicam

  • Pirprofen

  • Procarbazine

  • Propranolol

  • Propyphenazone

  • Proquazone

  • Psyllium

  • Rifampin

  • Selegiline

  • Sotalol

  • Sulindac

  • Suprofen

  • Talinolol

  • Tenidap

  • Tenoxicam

  • Tertatolol

  • Tiaprofenic Acid

  • Timolol

  • Tolmetin

  • Toloxatone

  • Tranylcypromine

  • Trimethoprim

  • Zomepirac

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of rosiglitazone and glimepiride. Make sure you tell your doctor if you have any other medical problems, especially:


  • Adrenal gland problem (underactive) or

  • Glucose 6-phosphate dehydrogenase (G6PD) deficiency (an enzyme problem), history of or

  • Kidney problems or

  • Pituitary gland problem (underactive) or

  • Poorly nourished condition or

  • Weakened physical condition—Use with caution. May cause side effects to become worse.

  • Angina, severe and acute or

  • Diabetic ketoacidosis (ketones in the blood) or

  • Heart attack, acute or

  • Heart failure, severe or with symptoms or

  • Liver disease, active or

  • Type 1 diabetes—Should not be used in patients with these conditions.

  • Diabetic macular edema (swelling of the back of the eye) or

  • Edema (fluid retention or swelling) or

  • Heart attack, history of or

  • Heart disease, history of or

  • Liver disease—Use with caution. May make these conditions worse.

  • Fever or

  • Infection or

  • Surgery or

  • Trauma—Use with caution. These conditions may cause problems with blood sugar control.

  • Fragile bones (especially in women)—Use with caution. rosiglitazone and glimepiride may increase the risk for fractures.

Proper Use of rosiglitazone and glimepiride


Take rosiglitazone and glimepiride only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.


Carefully follow the special diet your doctor gave you. This is the most important part of controlling your diabetes and will help the medicine work properly. Also, exercise regularly and test for sugar in your blood or urine as directed.


rosiglitazone and glimepiride is only available through a restricted access program. Both you and your doctor must enroll in this program. You might have to sign a consent form in order to receive rosiglitazone and glimepiride and your doctor will closely monitor your progress while you are taking rosiglitazone and glimepiride. Talk to your doctor if you have questions about this.


rosiglitazone and glimepiride should come with a Medication Guide. It is very important that you read and understand this information. Be sure to ask your doctor about anything you do not understand.


rosiglitazone and glimepiride should be taken with the first meal of the day.


Dosing


The dose of rosiglitazone and glimepiride will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of rosiglitazone and glimepiride. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For oral dosage form (tablets):
    • For type 2 diabetes:
      • For patients already taking glimepiride or rosiglitazone alone:
        • Adults—At first, rosiglitazone 4 milligrams (mg) plus glimepiride 1 mg or rosiglitazone 4 mg plus glimepiride 2 mg once a day, as directed by your doctor. Your doctor may adjust your dose as needed. However, the dose is usually not more than rosiglitazone 8 mg plus glimepiride 4 mg per day.

        • Children—Use and dose must be determined by your doctor.


      • For patients switching from a combination of glimepiride and rosiglitazone as separate tablets:
        • Adults—The dose is the same as the dose you are already taking. Your doctor may adjust your dose as needed. However, the dose is usually not more than rosiglitazone 8 mg plus glimepiride 4 mg per day.

        • Children—Use and dose must be determined by your doctor.




Missed Dose


If you miss a dose of rosiglitazone and glimepiride, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using rosiglitazone and glimepiride


It is very important that your doctor check your progress at regular visits to make sure that rosiglitazone and glimepiride is working properly. Blood and urine tests may be needed to check for unwanted effects.


Call your doctor right away if you have chest pain or discomfort; nausea; pain or discomfort in the arms, jaw, back, or neck; shortness of breath; sweating; or vomiting. These may be symptoms of a heart attack.


If you are rapidly gaining weight or having shortness of breath, chest pain or discomfort, extreme tiredness or weakness, irregular breathing, irregular heartbeat, or excessive swelling of the hands, wrist, ankles, or feet, check with your doctor right away. These may be symptoms of a heart problem or edema (fluid retention).


If you have abdominal or stomach pain; dark urine; a loss of appetite; nausea or vomiting; unusual tiredness or weakness; or yellow eyes or skin, check with your doctor right away. These may be symptoms of a serious liver problem.


Check with your doctor right away if blurred vision, difficulty in reading, or any other change in vision occurs while you are taking rosiglitazone and glimepiride. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).


rosiglitazone and glimepiride may increase the risk for bone fractures in women. Ask your doctor about ways to keep your bones strong to help prevent fractures.


Certain women may be at an increased risk for pregnancy while taking rosiglitazone and glimepiride. If you had problems ovulating and had irregular periods in the past, rosiglitazone and glimepiride may cause you to ovulate. This could increase your chance of becoming pregnant. If you are a woman of childbearing potential, you should discuss birth control options with your doctor.


rosiglitazone and glimepiride may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.


Make sure any doctor or dentist who treats you knows that you are using rosiglitazone and glimepiride. rosiglitazone and glimepiride may affect the results of certain medical tests.


It is very important to carefully follow any instructions from your doctor about:


  • Alcohol—Drinking alcohol may cause severe low blood sugar. Discuss this with your doctor.

  • Other medicines—Do not take other medicines unless they have been discussed with your doctor. This especially includes nonprescription medicines such as aspirin, and medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems.

  • Counseling—Other family members need to learn how to prevent side effects or help with side effects if they occur. Also, diabetic patients may need special counseling about diabetes medicine dosing changes that might occur because of lifestyle changes, such as changes in exercise and diet. Furthermore, counseling on contraception and pregnancy may be needed because of the problems that can occur in patients with diabetes during pregnancy.

  • Travel—Keep a recent prescription and your medical history with you. Be prepared for an emergency as you would normally. Make allowances for changing time zones and keep your meal times as close as possible to your usual meal times.

  • In case of emergency—There may be a time when you need emergency help for a problem caused by your diabetes. You need to be prepared for these emergencies. It is a good idea to wear a medical identification (ID) bracelet or neck chain at all times. Also, carry an ID card in your wallet or purse that says that you have diabetes and a list of all of your medicines.

  • Symptoms of fluid retention—Know what to do if you start to retain fluid. Fluid retention may worsen or lead to heart problems.

rosiglitazone and glimepiride can cause hypoglycemia (low blood sugar). Low blood sugar can also occur if you delay or miss a meal or snack, exercise more than usual, drink alcohol, or cannot eat because of nausea or vomiting. The symptoms of low blood sugar must be treated before they lead to unconsciousness (passing out). Different people feel different symptoms of low blood sugar. It is important that you learn which symptoms of low blood sugar you usually have so that you can treat it quickly.


  • Symptoms of low blood sugar include anxiety; behavior change similar to being drunk; blurred vision; cold sweats; confusion; cool, pale skin; difficulty in thinking; drowsiness; excessive hunger; fast heartbeat; headache (continuing); nausea; nervousness; nightmares; restless sleep; shakiness; slurred speech; or unusual tiredness or weakness.

  • If symptoms of low blood sugar occur, eat glucose tablets or gel, corn syrup, honey, or sugar cubes; or drink fruit juice, non-diet soft drinks, or sugar dissolved in water to relieve the symptoms. Also, check your blood for low blood sugar. Glucagon is used in emergency situations when severe symptoms such as seizures (convulsions) or unconsciousness occur. Have a glucagon kit available, along with a syringe and needle, and know how to use it. Members of your family also should know how to use it.

Hyperglycemia (high blood sugar) may occur if you do not take enough or skip a dose of your medicine, overeat or do not follow your meal plan, have a fever or infection, or do not exercise as much as usual.


  • Symptoms of high blood sugar include blurred vision; drowsiness; dry mouth; flushed, dry skin; fruit-like breath odor; increased urination (frequency and amount); ketones in the urine; loss of appetite; sleepiness; stomachache, nausea, or vomiting; tiredness; troubled breathing (rapid and deep); unconsciousness; or unusual thirst.

  • If the symptoms of high blood sugar occur, check your blood sugar level and call your doctor for instructions.

rosiglitazone and glimepiride Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


More common
  • Body aches or pain

  • chills

  • cough

  • difficulty with breathing

  • ear congestion

  • fever

  • headache

  • injury

  • loss of voice

  • nasal congestion

  • runny nose

  • sneezing

  • sore throat

  • unusual tiredness or weakness

Less common
  • Anxiety

  • blurred vision

  • chest pain or discomfort

  • cold sweats

  • coma

  • confusion

  • cool, pale skin

  • decreased urine output

  • depression

  • dilated neck veins

  • dizziness

  • extreme fatigue

  • fast heartbeat

  • increased hunger

  • irregular breathing

  • irregular heartbeat

  • nausea

  • nervousness

  • nightmares

  • seizures

  • shakiness

  • shortness of breath

  • slurred speech

  • swelling of the face, fingers, feet, or lower legs

  • tightness in the chest

  • troubled breathing with exertion

  • unusual bleeding or bruising

  • weight gain

  • wheezing

Incidence not known
  • Abdominal or stomach pain or tenderness

  • agitation

  • back, leg, or stomach pains

  • bleeding gums

  • bloody, black, or tarry stools

  • blue lips and fingernails

  • coughing that sometimes produces a pink frothy sputum

  • dark urine

  • decreased appetite

  • difficult, fast, or noisy breathing, sometimes with wheezing

  • fluid-filled skin blisters

  • general body swelling

  • hostility

  • increased sweating

  • increased thirst

  • irritability

  • itching

  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

  • lethargy

  • light-colored stools

  • loss of appetite

  • muscle pain or cramps

  • muscle twitching

  • nosebleeds

  • pain or discomfort in the arms, jaw, back, or neck

  • redness of the skin

  • seizures

  • sensitivity to the sun

  • skin rash

  • skin thinness

  • sores, ulcers, or white spots on the lips or in the mouth

  • stupor

  • sweating

  • swollen glands

  • vomiting

  • yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Less common
  • Lack or loss of strength

Rare
  • Burning, stinging, itching, or redness of the skin not present before therapy

Incidence not known
  • Diarrhea

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: rosiglitazone and glimepiride side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More rosiglitazone and glimepiride resources


  • Rosiglitazone and glimepiride Side Effects (in more detail)
  • Rosiglitazone and glimepiride Dosage
  • Rosiglitazone and glimepiride Use in Pregnancy & Breastfeeding
  • Rosiglitazone and glimepiride Drug Interactions
  • Rosiglitazone and glimepiride Support Group
  • 1 Review for Rosiglitazone and glimepiride - Add your own review/rating


Compare rosiglitazone and glimepiride with other medications


  • Diabetes, Type 2

Thursday, 13 October 2011

Lisdexamfetamine




In the US, Lisdexamfetamine (lisdexamfetamine systemic) is a member of the drug class CNS stimulants and is used to treat ADHD, Asperger Syndrome, Chronic Fatigue Syndrome, Narcolepsy and Oppositional Defiant Disorder.

US matches:

  • Lisdexamfetamine

  • Lisdexamfetamine dimesylate

Scheme

Rec.INN

CAS registry number (Chemical Abstracts Service)

0608137-32-2

Chemical Formula

C15-H25-N3-O

Molecular Weight

263

Therapeutic Category

Central stimulant

Chemical Names

(2S)-2,6-diamino-N-[(1S)-1-phenylpropan-2-yl]hexanamide (WHO)

(S)-2,6-Diaminhexansäure ((S)-1-methyl-2-phenylethyl)amid (IUPAC)

Foreign Names

  • Lisdexamfetaminum (Latin)
  • Lisdexamfetamin (German)
  • Lisdexamfetamine (French)
  • Lisdexamfetamina (Spanish)

Generic Names

  • NRP-104 (IS)
  • Lisdexamfetamine Dimesylate (OS: USAN)
  • amfetamine prodrug (IS)
  • LDX (IS)
  • lis-dexamfetamine dimesylate (IS)
  • L-lysine-d-amfetamine (IS)
  • NRP 104 (IS: NewRiverPharma)

Brand Name

  • Vyvanse
    Shire, United States

International Drug Name Search

Glossary

IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

Wednesday, 12 October 2011

Minipil




Minipil may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Minipil



Ethinylestradiol

Ethinylestradiol is reported as an ingredient of Minipil in the following countries:


  • Colombia

Levonorgestrel

Levonorgestrel is reported as an ingredient of Minipil in the following countries:


  • Colombia

Megestrol

Megestrol 17α-acetate (a derivative of Megestrol) is reported as an ingredient of Minipil in the following countries:


  • Netherlands

International Drug Name Search

Friday, 7 October 2011

Hexaler




Hexaler may be available in the countries listed below.


Ingredient matches for Hexaler



Desloratadine

Desloratadine is reported as an ingredient of Hexaler in the following countries:


  • Argentina

International Drug Name Search

Wednesday, 28 September 2011

Gallstone Ileus Medications


There are currently no drugs listed for "Gallstone Ileus".

Definition of Gallstone Ileus: Obstruction of the small intestine produced by passage of a gallstone from the biliary tract (usually the gallbladder as a result of cholecystitis) into the intestinal tract (usually by means of a fistulous connection between the gallbladder and the small intestine); occurrence and site of obstruction depend upon size of the stone, but the usual location is at or near the ileocaecal junction.

Learn more about Gallstone Ileus





Drug List:

Monday, 26 September 2011

Ketotifeno MK




Ketotifeno MK may be available in the countries listed below.


Ingredient matches for Ketotifeno MK



Ketotifen

Ketotifen is reported as an ingredient of Ketotifeno MK in the following countries:


  • Colombia

  • Ecuador

Ketotifen fumarate (a derivative of Ketotifen) is reported as an ingredient of Ketotifeno MK in the following countries:


  • Costa Rica

International Drug Name Search

Saturday, 24 September 2011

Berlex




Berlex may be available in the countries listed below.


Ingredient matches for Berlex



Alendronic Acid

Alendronic Acid is reported as an ingredient of Berlex in the following countries:


  • Argentina

International Drug Name Search

Thursday, 15 September 2011

Simvastatin AWD




Simvastatin AWD may be available in the countries listed below.


Ingredient matches for Simvastatin AWD



Simvastatin

Simvastatin is reported as an ingredient of Simvastatin AWD in the following countries:


  • Germany

International Drug Name Search

Dermacrin A




Dermacrin A may be available in the countries listed below.


Ingredient matches for Dermacrin A



Enoxolone

Enoxolone is reported as an ingredient of Dermacrin A in the following countries:


  • Japan

International Drug Name Search

Glycocolle




Glycocolle may be available in the countries listed below.


Ingredient matches for Glycocolle



Glycine

Glycine is reported as an ingredient of Glycocolle in the following countries:


  • Tunisia

International Drug Name Search

Tuesday, 6 September 2011

Sulfosept




Sulfosept may be available in the countries listed below.


Ingredient matches for Sulfosept



Zinc Sulfate

Zinc Sulfate is reported as an ingredient of Sulfosept in the following countries:


  • Slovakia

International Drug Name Search

Monotard HM




Monotard HM may be available in the countries listed below.


Ingredient matches for Monotard HM



Insulin Zinc Suspension (compound)

Insulin Zinc Suspension (compound) human (a derivative of Insulin Zinc Suspension (compound)) is reported as an ingredient of Monotard HM in the following countries:


  • Ethiopia

  • Greece

  • Guyana

  • India

  • Indonesia

  • Israel

  • Japan

  • Luxembourg

  • Serbia

International Drug Name Search

Saturday, 27 August 2011

Nüfro




Nüfro may be available in the countries listed below.


Ingredient matches for Nüfro



Nifuroxazide

Nifuroxazide is reported as an ingredient of Nüfro in the following countries:


  • Turkey

International Drug Name Search

Saturday, 20 August 2011

Tanap




Tanap may be available in the countries listed below.


Ingredient matches for Tanap



Trandolapril

Trandolapril is reported as an ingredient of Tanap in the following countries:


  • Czech Republic

International Drug Name Search

Octreotide




In some countries, this medicine may only be approved for veterinary use.


In the US, Octreotide (octreotide systemic) is a member of the drug class somatostatin and somatostatin analogs and is used to treat Acromegaly, Carcinoid Tumor, Diabetes - Type 1, Diarrhea, Gastrinoma, Glucagonoma, Insulinoma, Pituitary Adenoma, Small Bowel or Pancreatic Fistula and Vasoactive Intestinal Peptide Tumor.

US matches:

  • Octreotide

  • Octreotide Kit

  • Octreotide injectable

  • Octreotide Injection, Intramuscular

  • Octreotide Acetate

UK matches:

  • Octreotide Mayne
  • Octreotide 100microgram / ml solution for injection (SPC)
  • Octreotide 200micrograms / ml solution for injection (SPC)
  • Octreotide 50 micrograms/1 ml Solution for injection (SPC)
  • Octreotide 500 micrograms/1 ml Solution for Injection (SPC)
  • Octreotide 500micrograms / ml solution for injection (SPC)
  • Octreotide 50micrograms / ml solution for injection (SPC)
  • Octreotide Hospira 100 micrograms/1 ml Solution for Injection (SPC)

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

H01CB02

CAS registry number (Chemical Abstracts Service)

0083150-76-9

Chemical Formula

C49-H66-N10-O10-S2

Molecular Weight

1019

Therapeutic Categories

Hemostatic agent, gastrointestinal tract

Growth hormone release inhibiting hormone analogue (analogue of somatostatin)

Chemical Name

D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamido cyclic (2-7) disulfide

Foreign Names

  • Octreotidum (Latin)
  • Octreotid (German)
  • Octréotide (French)
  • Octreotida (Spanish)

Generic Names

  • Octreotide (OS: BAN, USAN)
  • Octréotide (OS: DCF)
  • SMS 201-995 (IS: Sandoz)
  • Octreotide Acetate (OS: BANM, JAN, USAN)
  • SMS 201-995 ac (IS)

Brand Names

  • Acrotid
    Sun Pharma, Peru


  • Azestan
    AC Farma, Peru


  • Cryostatin
    Cryopharma, Mexico


  • Longastatina
    Italfarmaco, Italy


  • Nomactril
    Ivax, Mexico


  • Octreotida Tosicina
    Support Pharma, Spain


  • Octreotide Mayne
    Hospira Nordic, Denmark


  • Octride
    Chalver, Colombia; Sun, Myanmar


  • Samilstin
    LPB, Italy


  • Sandostatin
    Novartis, Argentina; Novartis, Austria; Novartis, Bosnia & Herzegowina; Novartis, Bulgaria; Novartis, Chile; Novartis, Czech Republic; Novartis, Denmark; Novartis, Spain; Novartis, Greece; Novartis, Hong Kong; Novartis, Indonesia; Novartis, Ireland; Novartis, Israel; Novartis, India; Novartis, Iceland; Novartis, Luxembourg; Novartis, Latvia; Novartis, Malta; Novartis, Norway; Novartis, New Zealand; Novartis, Romania; Novartis, Serbia; Novartis, Russian Federation; Novartis, Thailand; Novartis, Turkey; Novartis, Taiwan; Novartis, Venezuela; Novartis, South Africa; Novartis Pharma, Vietnam; Novartis Pharmaceuticals, Peru


  • Sandostatin (veterinary use)
    Novartis Animal Health, United Kingdom


  • Sandostatin LAR
    Novartis, Australia; Novartis, Ecuador; Novartis, Indonesia; Novartis, Turkey; Novartis, Taiwan


  • Sandostatina
    Novartis, Italy; Novartis, Portugal


  • Sandostatine
    Novartis, Tunisia


  • Bendatreotid
    Bendalis, Germany


  • Longastatina LAR
    Italfarmaco, Italy


  • Octreotid Hexal
    Hexal, Germany


  • Octreotide Acetate
    APP, United States; Bedford, United States; Hospira, Australia; Sun, United States; Teva USA, United States


  • Octreotide Hospira
    Hospira, Netherlands; Hospira, Norway; Hospira, New Zealand; Hospira Nordic, Sweden


  • Octréotide Hospira
    Hospira, France


  • Octreotide Sandoz
    Sandoz, Netherlands


  • Octreotide
    Hospira, Italy


  • Sandostatin Euro
    Euro, Netherlands


  • Sandostatin
    Novartis, Australia; Novartis, Canada; Novartis, Switzerland; Novartis, China; Novartis, Germany; Novartis, Estonia; Novartis, Finland; Novartis, United Kingdom; Novartis, Georgia; Novartis, Croatia (Hrvatska); Novartis, Hungary; Novartis, Ireland; Novartis, Japan; Novartis, Sri Lanka; Novartis, Lithuania; Novartis, Malaysia; Novartis, Oman; Novartis, Philippines; Novartis, Poland; Novartis, Serbia; Novartis, Sweden; Novartis, Slovenia; Novartis, Slovakia; Novartis, United States


  • Sandostatin LAR
    Novartis, Argentina; Novartis, Austria; Novartis, Brazil; Novartis, Switzerland; Novartis, Chile; Novartis, China; Novartis, Colombia; Novartis, Czech Republic; Novartis, Germany; Novartis, Denmark; Novartis, Spain; Novartis, United Kingdom; Novartis, Hong Kong; Novartis, Croatia (Hrvatska); Novartis, Hungary; Novartis, Iceland; Novartis, Italy; Novartis, Japan; Novartis, Lithuania; Novartis, Luxembourg; Novartis, Malta; Novartis, Norway; Novartis, New Zealand; Novartis, Oman; Novartis, Poland; Novartis, Portugal; Novartis, Romania; Novartis, Serbia; Novartis, Russian Federation; Novartis, Sweden; Novartis, Singapore; Novartis, Slovenia; Novartis, United States; Novartis, Venezuela; Novartis Pharmaceuticals, Peru


  • Sandostatina LAR
    Novartis, Bulgaria


  • Sandostatine LAR
    Medcor, Netherlands; Novartis, Netherlands


  • Sandostatine
    EU-Pharma, Netherlands; Novartis, Belgium; Novartis, France; Novartis, Netherlands

International Drug Name Search

Glossary

BANBritish Approved Name
BANMBritish Approved Name (Modified)
DCFDénomination Commune Française
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
SPC Summary of Product Characteristics (UK)
USANUnited States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Thursday, 18 August 2011

Penbutololo




Penbutololo may be available in the countries listed below.


Ingredient matches for Penbutololo



Penbutolol

Penbutololo (DCIT) is known as Penbutolol in the US.

International Drug Name Search

Glossary

DCITDenominazione Comune Italiana

Click for further information on drug naming conventions and International Nonproprietary Names.

Wednesday, 17 August 2011

Velcox




Velcox may be available in the countries listed below.


Ingredient matches for Velcox



Meloxicam

Meloxicam is reported as an ingredient of Velcox in the following countries:


  • Indonesia

International Drug Name Search

Monday, 15 August 2011

AFI-D2 forte




AFI-D2 forte may be available in the countries listed below.


Ingredient matches for AFI-D2 forte



Ergocalciferol

Ergocalciferol is reported as an ingredient of AFI-D2 forte in the following countries:


  • Norway

International Drug Name Search

Sunday, 14 August 2011

Devodil




Devodil may be available in the countries listed below.


Ingredient matches for Devodil



Sulpiride

Sulpiride is reported as an ingredient of Devodil in the following countries:


  • Cyprus

  • Kenya

  • Sudan

  • Taiwan

  • Zimbabwe

International Drug Name Search

Thursday, 4 August 2011

Talwin




In some countries, this medicine may only be approved for veterinary use.


In the US, Talwin (pentazocine systemic) is a member of the drug class narcotic analgesics and is used to treat Anesthesia, Labor Pain, Pain and Sedation.

US matches:

  • Talwin

  • Talwin Nx

  • Talwin Lactate

Ingredient matches for Talwin



Pentazocine

Pentazocine hydrochloride (a derivative of Pentazocine) is reported as an ingredient of Talwin in the following countries:


  • Canada

Pentazocine lactate (a derivative of Pentazocine) is reported as an ingredient of Talwin in the following countries:


  • Canada

  • Israel

  • Italy

  • United States

International Drug Name Search

Sunday, 31 July 2011

Cibren




Cibren may be available in the countries listed below.


Ingredient matches for Cibren



Citicoline

Citicoline is reported as an ingredient of Cibren in the following countries:


  • Indonesia

International Drug Name Search

Wednesday, 27 July 2011

Phillips`Liqui-Gels




Ingredient matches for Phillips`Liqui-Gels



Docusate

Docusate Sodium is reported as an ingredient of Phillips`Liqui-Gels in the following countries:


  • United States

International Drug Name Search

Wednesday, 20 July 2011

Gentamicin Wagner




Gentamicin Wagner may be available in the countries listed below.


Ingredient matches for Gentamicin Wagner



Gentamicin

Gentamicin sulfate (a derivative of Gentamicin) is reported as an ingredient of Gentamicin Wagner in the following countries:


  • Hungary

International Drug Name Search

Monday, 18 July 2011

Avitrol Bird




Avitrol Bird may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Avitrol Bird



Piperonyl Butoxide

Piperonyl Butoxide is reported as an ingredient of Avitrol Bird in the following countries:


  • Australia

Pyrethrin I

Pyrethrin I is reported as an ingredient of Avitrol Bird in the following countries:


  • Australia

International Drug Name Search

Thursday, 14 July 2011

Tobradosa




Tobradosa may be available in the countries listed below.


Ingredient matches for Tobradosa



Tobramycin

Tobramycin is reported as an ingredient of Tobradosa in the following countries:


  • Argentina

International Drug Name Search

Rapivir




Rapivir may be available in the countries listed below.


Ingredient matches for Rapivir



Valacyclovir

Valaciclovir hydrochloride (a derivative of Valaciclovir) is reported as an ingredient of Rapivir in the following countries:


  • Mexico

International Drug Name Search

Wednesday, 13 July 2011

Tizoxim




Tizoxim may be available in the countries listed below.


Ingredient matches for Tizoxim



Cefotaxime

Cefotaxime sodium salt (a derivative of Cefotaxime) is reported as an ingredient of Tizoxim in the following countries:


  • Argentina

  • Peru

International Drug Name Search

Friday, 8 July 2011

Aspen Cefuroxime




Aspen Cefuroxime may be available in the countries listed below.


Ingredient matches for Aspen Cefuroxime



Cefuroxime

Cefuroxime sodium salt (a derivative of Cefuroxime) is reported as an ingredient of Aspen Cefuroxime in the following countries:


  • South Africa

International Drug Name Search

Saturday, 25 June 2011

Maxiclear Sinus Relief




Maxiclear Sinus Relief may be available in the countries listed below.


Ingredient matches for Maxiclear Sinus Relief



Phenylephrine

Phenylephrine hydrochloride (a derivative of Phenylephrine) is reported as an ingredient of Maxiclear Sinus Relief in the following countries:


  • New Zealand

International Drug Name Search

Sunday, 19 June 2011

Ephedronguent




Ephedronguent may be available in the countries listed below.


Ingredient matches for Ephedronguent



Ephedrine

Ephedrine hydrochloride (a derivative of Ephedrine) is reported as an ingredient of Ephedronguent in the following countries:


  • Belgium

International Drug Name Search

Saturday, 18 June 2011

Ubercet




Ubercet may be available in the countries listed below.


Ingredient matches for Ubercet



Cetirizine

Cetirizine dihydrochloride (a derivative of Cetirizine) is reported as an ingredient of Ubercet in the following countries:


  • Poland

International Drug Name Search

Friday, 17 June 2011

Oxypan




Oxypan may be available in the countries listed below.


Ingredient matches for Oxypan



Oxytetracycline

Oxytetracycline hydrochloride (a derivative of Oxytetracycline) is reported as an ingredient of Oxypan in the following countries:


  • South Africa

International Drug Name Search

Famultran




Famultran may be available in the countries listed below.


Ingredient matches for Famultran



Famotidine

Famotidine is reported as an ingredient of Famultran in the following countries:


  • Bulgaria

  • Georgia

International Drug Name Search

Tuesday, 14 June 2011

Remov




Remov may be available in the countries listed below.


Ingredient matches for Remov



Nimesulide

Nimesulide is reported as an ingredient of Remov in the following countries:


  • Italy

  • Malta

International Drug Name Search

Monday, 13 June 2011

Canitex




Canitex may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Canitex



Permethrin

Permethrin is reported as an ingredient of Canitex in the following countries:


  • Portugal

Pyrethrin I

Pyrethrin I is reported as an ingredient of Canitex in the following countries:


  • Portugal

International Drug Name Search

Sunday, 12 June 2011

Repaglinide/Metformin


Pronunciation: re-PAG-li-nide/met-FOR-min
Generic Name: Repaglinide/Metformin
Brand Name: PrandiMet

Repaglinide/Metformin may rarely cause a serious and sometimes fatal condition called lactic acidosis. Most of these cases have occurred in diabetic patients who also have certain kidney problems. The risk of lactic acidosis may be greater if you have liver problems, kidney problems, or heart failure. The risk may also be greater in patients who are elderly or drink alcohol. Lab tests, including kidney function, may be performed while you take Repaglinide/Metformin.


Do not begin to take Repaglinide/Metformin if you are older than 80 years old unless lab tests show that you do not have decreased kidney function. Do not take it if you have a severe infection, have low blood oxygen levels, or are dehydrated. Tell your doctor you take Repaglinide/Metformin before you have any surgery or lab procedures.


Contact your doctor right away if you notice symptoms such as muscle pain or tenderness; unusual drowsiness, dizziness, or lightheadedness; slow or irregular heartbeat; fast or difficult breathing; unusual stomach discomfort; or unusual weakness or tiredness. Contact your doctor right away if you start to feel unusually cold, or if you have a general feeling of being unwell.





Repaglinide/Metformin is used for:

Treating type 2 diabetes. It is used along with diet and exercise. It may be used alone or with other antidiabetic medicines.


Repaglinide/Metformin is a meglitinide and biguanide combination. It works by decreasing the amount of sugar absorbed from food by the intestines and reduces the amount of sugar made in the liver. It also increases the amount of insulin in the blood and helps your body to use insulin and sugar more efficiently. This helps to control blood sugar levels.


Do NOT use Repaglinide/Metformin if:


  • you are allergic to any ingredient in Repaglinide/Metformin

  • you have congestive heart failure that is treated by medicine

  • you have a severe infection, low blood oxygen levels, kidney or liver problems, high blood ketone or acid levels (eg, diabetic ketoacidosis), or severe dehydration

  • you have had a stroke or a recent heart attack, or you are in shock

  • you are 80 years old or older and have not had a kidney function test

  • you will be having surgery or certain lab procedures

  • you are taking gemfibrozil, gemfibrozil along with itraconazole, or NPH insulin

Contact your doctor or health care provider right away if any of these apply to you.



Before using Repaglinide/Metformin:


Some medical conditions may interact with Repaglinide/Metformin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of heart problems (eg, heart failure), lung or breathing problems, thyroid problems, stomach or bowel problems (eg, paralysis, blockage), adrenal or pituitary problems, or lactic acidosis

  • if you have diarrhea, poor health or nutrition, low blood calcium or vitamin B12 levels, or anemia, or if you are dehydrated or vomiting

  • if you have an infection, fever, recent injury, or moderate to severe burns

  • if you drink alcohol or have a history of alcohol abuse

  • if you will be having surgery or certain lab procedures

  • if you take a beta-blocker (eg, propranolol) or are using insulin

Some MEDICINES MAY INTERACT with Repaglinide/Metformin. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • NPH insulin because the risk of certain heart problems (eg, myocardial ischemia, chest pain) may be increased

  • Amiloride, cimetidine, digoxin, gemfibrozil, imidazoles (eg, ketoconazole), macrolides (eg, erythromycin), morphine, procainamide, quinidine, quinine, ranitidine, rofecoxib, telithromycin, triamterene, trimethoprim, or vancomycin because they may increase the risk of Repaglinide/Metformin's side effects

  • Beta-blockers (eg, propranolol), calcium channel blockers (eg, nifedipine), corticosteroids (eg, prednisone), cyclosporine, diuretics (eg, furosemide, hydrochlorothiazide), estrogen, hormonal contraceptives (eg, birth control pills), insulin, isoniazid, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), nicotinic acid, phenothiazine (eg, chlorpromazine), phenytoin, salicylates (eg, aspirin), sulfonylureas (eg, glipizide), sympathomimetics (eg, albuterol, pseudoephedrine), or thyroid hormones (eg, levothyroxine) because the risk of high or low blood sugar may be increased

  • Rifampin because it may decrease Repaglinide/Metformin's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Repaglinide/Metformin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Repaglinide/Metformin:


Use Repaglinide/Metformin as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • An extra patient leaflet is available with Repaglinide/Metformin. Talk to your pharmacist if you have questions about this information.

  • Take Repaglinide/Metformin by mouth at least 15 to 30 minutes before each meal. If you skip a meal, do not take the dose for the skipped meal.

  • Take Repaglinide/Metformin on a regular schedule to get the most benefit from it. Taking Repaglinide/Metformin at the same time each day will help you remember to take it.

  • Continue to take Repaglinide/Metformin even if you feel well. Do not miss any doses.

  • If you miss a dose of Repaglinide/Metformin, skip the missed dose and go back to your regular dosing schedule.

Ask your health care provider any questions you may have about how to use Repaglinide/Metformin.



Important safety information:


  • Dizziness may occur while you are taking Repaglinide/Metformin. This effect may be worse if you take it with alcohol or certain medicines. Use Repaglinide/Metformin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Follow the diet and exercise program given to you by your health care provider.

  • Do not drink large amounts of alcohol while you use Repaglinide/Metformin. Talk to your doctor or health care provider before you drink alcohol while you use Repaglinide/Metformin.

  • Tell your doctor or dentist that you take Repaglinide/Metformin before you receive any medical or dental care, emergency care, or surgery.

  • Be careful not to become dehydrated, especially during hot weather or while you are being active. Dehydration may increase the risk of Repaglinide/Metformin's side effects.

  • If vomiting or diarrhea occurs, you will need to take care not to become dehydrated. Contact your doctor for instructions.

  • Carry an ID card at all times that says you have diabetes. Check your blood sugar levels as directed by your doctor. If they are often higher or lower than they should be and you take Repaglinide/Metformin exactly as prescribed, tell your doctor.

  • Repaglinide/Metformin may cause low blood sugar. Low blood sugar may be more likely to occur if you skip a meal, exercise heavily, or drink alcohol. It may also be more likely if you take Repaglinide/Metformin along with certain medicines for diabetes (eg, sulfonylureas, insulin). It is a good idea to carry a reliable source of glucose (eg, tablets or gel) to treat low blood sugar. If this is not available, you should eat or drink a quick source of sugar like table sugar, honey, candy, orange juice, or non-diet soda. This will raise your blood sugar level quickly. Tell your doctor right away if this happens. To prevent low blood sugar, eat meals at the same time each day and do not skip meals.

  • Fever, infection, injury, or surgery may increase your risk for high or low blood sugar levels. If any of these occur, check your blood sugar closely and tell your doctor right away.

  • Repaglinide/Metformin may commonly cause stomach upset, indigestion, nausea, vomiting, or diarrhea at the beginning of treatment. If you develop unusual or unexpected stomach problems, or if you develop stomach problems later during treatment, contact your doctor at once. This may be a sign of lactic acidosis.

  • Lab tests, including kidney function, fasting blood glucose, hemoglobin A1c, and blood counts, may be performed while you use Repaglinide/Metformin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Repaglinide/Metformin with caution in the ELDERLY; they may be more sensitive to its effects. Low blood sugar levels may also be more difficult to recognize in the elderly.

  • Repaglinide/Metformin should not be used in CHILDREN; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Repaglinide/Metformin while you are pregnant. Repaglinide/Metformin is found in breast milk. Do not breast-feed while taking Repaglinide/Metformin.

When used for long periods of time, Repaglinide/Metformin may not work as well. If your blood sugar has been under control and then becomes hard to manage, contact your doctor. Do not change the dose of your medicine without checking with your doctor.



Possible side effects of Repaglinide/Metformin:


All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Diarrhea; gas; headache; indigestion; nausea; stomach upset; temporary metallic taste; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain or discomfort; dark urine; dizziness or lightheadedness; fast or difficult breathing; feeling of being unusually cold; fever, chills, or persistent sore throat; general feeling of being unwell; muscle pain or weakness; slow or irregular heartbeat; unusual drowsiness; unusual or persistent stomach pain or discomfort; unusual tiredness or weakness; yellowing of the skin or eyes.



This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.



If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include dizziness or lightheadedness; fast or difficult breathing; feeling of being unusually cold; general feeling of being unwell; muscle pain or tenderness; slow or irregular heartbeat; unusual drowsiness; unusual stomach discomfort; unusual weakness or tiredness.


Proper storage of Repaglinide/Metformin:

Store Repaglinide/Metformin at 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Repaglinide/Metformin out of the reach of children and away from pets.


General information:


  • If you have any questions about Repaglinide/Metformin, please talk with your doctor, pharmacist, or other health care provider.

  • Repaglinide/Metformin is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Repaglinide/Metformin. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Repaglinide/Metformin resources


  • Repaglinide/Metformin Dosage
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  • Repaglinide/Metformin Drug Interactions
  • Repaglinide/Metformin Support Group
  • 0 Reviews for Repaglinide/Metformin - Add your own review/rating


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